Zolppi L Capsule

Rabeprazole sodium Levosulpride Tablet


Each ZOLPPI L capsule contains rabeprazole sodium (EG) 20mg and levosulpiride (SR) 75mg


ZOLPPI L is the combination of two powerful anti-ulcerants which address various complications associated with the acid-reflux issues and Helicobacter pylori infections.

Rabeprazole, which is a substituted benzimidazole, works as a proton pump inhibitor (PPI). Rabeprazole is activated in the acidic environment only. Rabeprazole gets absorbed by the parietal cells. After the activation, this drug binds to the H+/ K+ ATPase system present on the parietal cells and blocks the inward movement of H+ ions into the stomach and prevents the last step of acid production.

Levosulpiride possesses strong gastrointestinal motility properties due to which it is used as a digestive aid. Levosulpiride specifically blocks D2 receptors of dopamine both at central and peripheral levels. This drug does not have any effect on acetylcholine, serotonin, histamine, and GABA receptors.


  • Helicobacter pylori infection and eradication
  • Heartburn
  • Gastroesophageal Reflux Disease (GERD)
  • Non-erosive Reflux Disease (NERD)
  • Zollinger-Ellison Syndrome
  • Duodenal and gastric ulcers
  • Irritable bowel syndrome

Dosage and Administration:

As directed by the physician


ZOLPPI L capsules are contraindicated in patients with hypersensitivity towards rabeprazole and levosulpiride. It is also contraindicated in patients with epilepsy, cardiac disorders, GI bleeding, malignant mastopathy, mammary dysplasia and hyperprolactinaemia.

Adverse effects:

Adverse effects of this medicine include sore throat, weakness, rashes, upset stomach and irregular periods.


There are no sufficient and well-controlled studies when it comes to rabeprazole and levosulpiride administration in pregnant women and nursing mothers. Therefore, if you are pregnant or nursing, discuss with your doctor about your condition before taking this medicine.


ZOLPPI L capsules are available in 10X1X10’s Alu Alu packing.


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Keep the medicines out of the children’s reach. This product is to be stored as recommended. Do not exceed the recommended dosage. Do not use this information in place of a visit, consultation or advice of your healthcare providers.