OSFOL-XT Tablets

Methylcobalamin 1500mg tablets


  • Methylcobalmine - 1.5 mg
  • L-Methylfolate - 1 mg
  • Pyridoxal-5-Phosphate - 0.5 mg


Osfol-XT contains L-Methylfolate, a natural, active form of folic acid, Methycobalmine, water soluble form of Vitamin B12, and Pyridoxal-5-Phosphate, active form of vitamin B6.

Methylcobalmine is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.

L-Methylfolate, unlike regular folic acid, it does not require enzymatic conversion to L-methylfolate in the body. By providing L-methylfolate directly, this form of folic acid may have benefits for those who do not produce enough L-methylfolate in response to folic acid supplementation. For those who take proper doses of folic acid, vitamins B12 and B6, and TMG (trimethylglycine), but still suffer from higher-than-optimal homocysteine, L-Methylfolate may be the solution.

Pyridoxal-5-phosphate is used by many enzymes. It is readily absorbed by the intestine by a process which is preceded by dephosphorylation to form pyridoxal. It helps metabolize homocysteine to cysteine. Elevated serum levels of homocysteine (hyperhomocysteinemia) increase the risk of diabetic complications, such as peripheral neuropathy and the related complaints of numbness, tingling, and burning sensations and nonhealing foot ulcers.


  • Folate-deficient Megaloblastic anaemia.
  • Prophylaxis of megaloblastic anemia in pregnancy.
  • Prophylaxis of neural tube defect in pregnancy.
  • Malabsorption syndromes.
  • Antiepileptic therapy
  • Peripheral neuropathies
  • Hyperhomocystenemia


As directed by the dietician, as per RDA value.


Undiagnosed megaloblastic anaemia, Pernicious ,Aplastic or normocytic anaemias


Treatment resistance may occur in patients with depressed haematopoiesis, alcoholism, deficiencies of other vitamins.


Generally Osfol-XT is tolerated well. There might be minimal adverse events such asanorexia, nausea, vomiting and diarrhea..


Osfol-XT is recommended as folate is especially important for pregnant women. Healthy levels of the vitamin can even lower the risks of certain birth defects.


Osfol-XT Tablet is available in blister of 10X1X10 tablets.


Always read the product directions before use. Do not exceed the recommended intake. As with other supplements, seek professional advice before using if you suffer from food allergies. Vitamin supplements are not intended to treat or prevent any disease. Food supplements must not replace a balanced and varied diet and a healthy lifestyle. Properly discard this supplement when it is expired or no longer needed.