Each NEVICAL FORTE softgel capsule contains



Calcium carbonate IP


Calcitriol IP


Methylcobalamin JP


Omega-3-Acid EthylEsters -60 BP providing: Eicosapentaenoic acid(EPA) 90mg, Docosahexaenoic acid(DHA) 60mg

Folic acid IP


Disodium tetraborate(eq. to elemental boron) BP



NEVICAL FORTE is a bone and joint health-supporting combination of minerals, vitamins and omega 3 fatty acids. These nutrients synergistically work towards improving bone health by enhancing calcium absorption, reducing the risk of bone damage and bone disorders and reducing inflammation. NEVICAL FORTE is helpful in the treatment of joint inflammation, osteoporosis, different types of arthritis, osteopenia, etc.

Reduced bone density is one of the common problems in individuals who are above 40-50 years old and this happens largely due to impaired calcium absorption in the body. NEVICAL FORTE contains calcium along with the active form of vitamin D3 – calcitriol, which helps in optimizing the calcium absorption. Boron and Omega-3 fatty acids keep the joints lubricated, while methylcobalamin and folic acid are helpful in reducing the risk of fractures and bone damage by regulating the homocysteine levels.

Key functions of NEVICAL FORTE:

  • Supports the structure and functioning of the bones
  • Keeps the joints well-lubricated and reduces the risk of bone breakage and fractures.
  • Promotes joint flexibility and mobility
  • Improves calcium absorption
  • Reduces the risk of folate-deficient megaloblastic anemia
  • Maintains the integrity of the bone structure and joints
  • Provides strength, stability and elasticity to the cartilage, tendons and ligaments

Calcium is highly essential for the bone remodeling process that takes place throughout the lifetime. And, not only do the bones need calcium; but vital organs such as kidneys, heart, and nerves also need calcium for their normal functioning. As a trace element, calcium regulates the pH balance and maintains a healthy alkaline pH. Absorption of calcium takes place in the small intestine in presence of vitamin D; thus, the former must always be supplemented along with vitamin D3 (calcitriol). Apart from serving as the key component of bones, its other functions include:

  • Calcium promotes fat loss by stimulating the usage of fat as a fuel for energy production
  • Calcium is necessary for the transport of vital nutrients throughout the body
  • Calcium supplements alleviate the symptoms of inflammation
  • Calcium regulates the blood pressure

Calcitriol is the active form of cholecalciferol (vitamin D3). Calcitriol has multiple biological functionswithin the body with respect to the bone health and the major ones include:

  • Increasing absorption of calcium from the GI tract
  • Enhancing renal tubular reabsorption of calcium and thereby bringing down the calcium levels in the urine
  • Increasing the absorption of phosphate in the intestine
  • Reducing the blood calcium levels by regulating the release of calcium from bones

Methylcobalamin and Folic acid are helpful in reducing the risk of bone fractures that are caused due to increased levels of homocysteine in the serum. High levels of serum homocysteine are also found to be associated with joint inflammation. Methylcobalamin and folic acid convert homocysteine to methionine via remethylation process and thereby help in protecting the bones and joints. Folic acid is also reported to relieve the pain and swelling associated with different types of arthritis. Vitamin B12, on the other hand, has an active role in the bone mineralization process and in bringing down the severity of inflammation in the joints.

Omega 3 fatty acids are helpful in bringing down the inflammation and the reactions associated with it. EPA and DHA increase the levels of anti-inflammatory markers such as TGF-ß and IL-10 and control the severity of inflammation. These are also found to delay the progression of osteoarthritis by decreasing the levels of enzymes that are responsible for cartilage degradation. EPA and DHA alleviate various symptoms associated with the inflammation namely, morning stiffness, tenderness, swelling and pain. These fatty acids improve the elasticity and mobility of the joints by signal transduction, gene expression alteration and by altering the eicosanoid biosynthesis pathway.

Boron is reported to have an active role in increasing the absorption, utilization and metabolism of vitamin D3, calcium and magnesium. As a trace element, it triggers bone mineralization process, enhances the wound healing abilities, reduces the levels of inflammatory markers in the serum and lastly increases the levels of antioxidants in order to neutralize the free radicals at the site of inflammation.


As directed by the physician


NEVICAL FORTE is contraindicated in patients with hypersensitivity towards its ingredients.


NEVICAL FORTE is well-tolerated when administered as per the recommended dosage. However, the rare adverse effects of this product include, nausea, diarrhea, constipation, upset stomach, increased thirst and urination, vomiting, loss of appetite and headache


Pregnant women, nursing mothers and individuals with known medical conditions are advised to discuss with the healthcare professional regarding their condition before consuming this product.


NEVICAL FORTE softgels are available in 3X10’s blister packing.


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Keep the medicines out of the children’s reach. This product is to be stored as recommended. Do not exceed the recommended dosage. Do not use this information in place of a visit, consultation or advice of your healthcare providers.