Each NEOMENTIN-CV tablet contains amoxicillin 500mg & clavulanic acid 125mg.
NEOMENTIN-CV is the brand name for the anti-bacterial combination of the beta-lactam antibiotic, amoxicillin and a beta-lactamase inhibitor, clavulanic acid. NEOMENTIN CV addresses various bacterial infections such as respiratory tract infections, skin infections and genitourinary tract infections.
Amoxicillin is a beta-lactam antibiotic that is derived from ampicillin. Amoxicillin’s mechanism of action involves inhibition of peptidoglycan synthesis in the bacterial cells. Amoxicillin binds to transpeptidase enzyme, which is involved in the third and final step of cell wall formation and prevents the cross-linking reaction in the bacterial cell wall. This increases the permeability of the cells and cell contents begin to leak; this eventually leads to the death of the bacterial cells.
Amoxicillin has a broad spectrum activity against Gram +ve and Gram-ve bacteria, but, it is highly susceptible to the beta-lactamase activity. Therefore, it has to be administered in combination with a beta-lactamase inhibitor like clavulanic acid. Clavulanic acid, which also possesses a beta-lactam ring, prevents the enzymatic degradation of amoxicillin, by binding to the beta-lactamase enzyme that is present in the bacterial cell wall.
As directed by the physician
NEOMENTIN-CV is contraindicated in patients with hypersensitivity towards amoxicillin, clavulanic acid and other beta-lactam antibiotics. It is also contraindicated in patients with renal impairment, liver disorders, Clostridium difficile infection, asthma, seizure disorders and jaundice.
Adverse effects of this medicine include diarrhea, nausea, vomiting, abdominal pain, dark urine, sore throat and unusual tiredness.
There are no sufficient and well-controlled studies when it comes to amoxicillin and clavulanic acid administration in pregnant women and nursing mothers. Therefore, if you are pregnant or nursing, discuss with your doctor about your condition before taking this medicine.
NEOMENTIN-CV tablets are available in 10X1X6’s Alu Alu packing.
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Keep the medicines out of the children’s reach. This product is to be stored as recommended. Do not exceed the recommended dosage. Do not use this information in place of a visit, consultation or advice of your healthcare providers.