Pantoprazole is a synthetic proton pump inhibitor that belongs to the class of substituted benzimidazoles and functions as a long-lasting inhibitor of gastric acid secretion. This drug is used in the treatment of different types of ulcers. High levels of stomach acid lead to several complications such as difficulty in swallowing, persistent cough, sleeplessness, and heartburn. Proton pump inhibition is considered to be the best form of treatment for ulcers because blocking the proton pump would prevent the acid formation and alleviate the above-mentioned symptoms, at a faster rate.
Pantoprazole prevents the gastric acid secretion in the stomach by blocking the proton pumps of the parietal cells. Pantoprazoleis activated in the acidic environment. Once it is activated in the parietal cells, pantoprazole inhibits the activity of H+ /K+ ATPase, an enzyme which acidifies the stomach by causing the influx of hydrogen ions into the stomach. Pantoprazole is exclusively metabolized in the hepatic system. In most cases, the symptoms are alleviated in 2 weeks’ time.
This medicine should be administered under medical supervision only.
FORPPI injection is contraindicated in patients with hypersensitivity towards pantoprazole or any other substituted benzimidazoles. This medicine is also contraindicated in patients with liver disorders, low levels of magnesium in the blood, heart diseases and osteoporosis.
Adverse effects of this medicine include headache, nausea, vomiting, GI disturbances, dizziness, drowsiness, blurred vision, sweating, unexplained weight loss and troubled breathing.
There are no sufficient and well-controlled studies when it comes to pantoprazole administration in pregnant women and nursing mothers. Therefore, if you are pregnant or nursing, discuss with your doctor about your condition before taking this medicine.
FORPPI injection is available in 10mL& 10mL NACL pack
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