Each FORPPI-DSR capsule contains pantoprazole 40mg and domperidone 30mg.
FORPPI-DSR is the brand name for the anti-ulcerant and antiemetic combination that effectively treats various complications that are associated with acid reflux and ulcers.
Pantoprazole is an efficient proton pump inhibitor that belongs to substituted benzimidazole class. Like other proton pump inhibitors, pantoprazole blocks the H+/K+ ATPase enzyme system or the proton pump system present on the gastric parietal cells. Proton pump inhibitors are activated in the acidic environment only. This drug prevents the final step of gastric acid production, i.e., the inward movement of H+ ions into the gastric lumen, and eventually reduces the levels of gastric acid and its reflux towards the chest region.
Domperidone is a potent anti-emetic agent that addresses nausea and vomiting along with the suppression of acid-reflux. On peripheral levels, it increases the lower esophageal pressure, improves the motility in the upper GI tract or peristalsis. It acts as an antagonist of D2 and D3 dopamine receptors in the area postrema, where lies the chemoreceptor trigger zone for nausea and vomiting.
As directed by the physician
FORPPI-DSR is contraindicated in patients with hypersensitivity towards pantoprazole and domperidone. This medicine is also contraindicated in patients with hepatic and renal impairment, interstitial nephritis, congestive heart failure and Clostridium difficile infections.
Adverse effects of this medicine include headache, dizziness, blurred vision, diarrhea, severe itching in the skin, nausea, flatulence, dry mouth, rashes and swelling.
There are no sufficient and well-controlled studies when it comes to pantoprazole and domperidone administration in pregnant women and nursing mothers. Therefore, if you are pregnant or nursing, discuss with your doctor about your condition before taking this medicine.
FORPPI-DSR capsules are available in 10X10’s Alu Alu packing.
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Keep the medicines out of the children’s reach. This product is to be stored as recommended. Do not exceed the recommended dosage. Do not use this information in place of a visit, consultation or advice of your healthcare providers.