Each 5mL of FENPILL PLUS suspension contains aceclofenac 50mg and paracetamol 125 mg.
FENPILL PLUS is the brand name for the anti-inflammatory and analgesic combination, which treats mild to moderate pain, fever and the common cold. The combination of aceclofenac and paracetamol is observed to be more effective than either drug alone.
Aceclofenac belongs to the class of non-steroidal anti-inflammatory drug. It is an analog of the drug, diclofenac. Aceclofenac blocks the activity of the enzyme, cyclooxygenase (COX) and consequently prevents the synthesis of prostaglandin and other inflammatory mediators. It is also a cytokine inhibitor and reduces the levels of reactive oxygen species (ROS) at the site of infection. All these cascading reactions will eventually reduce the pain and swelling at the site of inflammation.
Paracetamolís exact mechanism of action is not known; however, it is strongly associated with the cyclooxygenase pathway. Paracetamol relieves inflammation-induced pain by increasing the pain threshold. It inhibits the prostaglandin synthesis in the brain.
As directed by the physician
FENPILL PLUS suspension is contraindicated in patients with hypersensitivity towards aceclofenac and paracetamol. This medication is also contraindicated in patients with gastrointestinal bleeding, heart failure, hypertension, hepatic impairment and renal impairment.
FENPILL PLUS suspension is contraindicated in pregnant and nursing women.
Adverse effects of this medicine are an upset stomach, dizziness, headache, heartburn, bloating, ulcers, constipation, diarrhea, rashes and itching.
Patients with platelet defects should avoid consuming NSAIDs. This medicine should not be combined with anticoagulants.
FENPILL PLUS SUSPENSION is available in 60mL bottle.
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