Each 5mL of DOXPORIN dry syrup contains cefpodoxime 50mg.
DOXPORIN DS is the brand name for the dry syrup formulation of the antibiotic cefpodoxime. Cefpodoxime is a beta-lactam antibiotic that belongs to the class of third-generation cephalosporins. This drug is active against several Gram +ve and Gram-ve bacteria. This drug is resistant to the activity of cephalosporinases, penicillinases and a few beta-lactamases.
Cefpodoxime works by inhibiting the cell wall synthesis in bacteria. This drug binds to the Penicillin Binding Protein 3, which inhibits the transpeptidation step of peptidoglycan synthesis in bacteria. This transpeptidation step is crucial for the cross-linking in the bacterial cell wall and without this cross-linking the bacterial cells cannot hold their content within them. This leakage will eventually lead to the death of the bacterial cells.
As directed by the physician
DOXPORIN dry syrup is contraindicated in patients with hypersensitivity towards cefpodoxime, Clostridium difficile infection, hepatic impairment and renal impairment
Adverse effects of this medicine include GI disturbances, nausea, vomiting, diarrhea, rashes and itching.
There are no sufficient and well-controlled studies when it comes to cefpodoxime administration in pregnant women and nursing mothers. Therefore, if you are pregnant or nursing, discuss with your doctor about your condition before taking this medicine.
DOXPORIN dry syrup is available in 30mL bottle with carton.
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