Diclofenac sodium 75mg
Diclofenac belongs to the category of non-steroidal anti-inflammatory drugs (NSAIDs) and is used to treat inflammation and its symptoms. Diclofenac also exhibits antipyretic, analgesic and bacteriostatic activity. This drug works by blocking the activity of the biochemical components that are responsible for causing pain, edema, erythema and high temperature.
Diclofenac sodium is a phenylacetic acid derivative, which works by inhibiting the enzyme cyclooxygenase (COX) or prostaglandin-endoperoxide synthase-2(PGES-2). This enzyme is responsible for the prostaglandin synthesis and other chemicals that cause inflammation and fever. Prostaglandin is one of the key mediators of inflammation and inhibiting its synthesis will bring down its levels in the peripheral tissue and thereby reduce the inflammation. Diclofenac is exclusively metabolized in the liver.
This medicine has to be administered under medical supervision only.
DOLET injection is contraindicated in patients with hypersensitivity towards its ingredients. It is also contraindicated in patients with asthma, urticaria, anemia, increased risk of bleeding, high blood pressure, chronic heart failure, stroke, blood clot, different types of ulcers, liver problems, GI bleeding and kidney diseases.
Adverse effects of this medication are nausea, vomiting, diarrhea, ulceration, headache, dizziness, vertigo and allergic reactions such as rashes, burning and itching.
There are no sufficient and well-controlled studies when it comes to diclofenac administration in pregnant women and nursing mothers. Therefore, if you are pregnant or nursing, discuss with your doctor about your condition before taking this medicine.
DOLET injection is available in 10x1mL Tray Pack
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