Dobex 250 Injection

Ceftriaxone 250 mg Injection


Ceftriaxone 250 mg


DOBEX 250 is the brand name for the antibiotic agent ceftriaxone. Ceftriaxone is one of the most powerful antibiotics that belong to the class of third-generation cephalosporins, with high penetrability and longer half-life.

Ceftriaxone is a beta-lactam antibiotic that works by inhibiting the synthesis and assembly of the bacterial cell wall. This antibiotic binds to the Penicillin Binding Proteins (PBPs) that are present in the bacterial cell wall and blocks the transpeptidation step of the peptidoglycan synthesis. Impaired cell wall synthesis will lead to leakage of the cell content and eventually cause the death of the bacteria.


  • Community-acquired pneumonia
  • Congenital gonococcal conjunctivitis
  • Endocarditis
  • Gonorrhea
  • Lyme disease
  • Meningitis
  • Otitis Media
  • Pelvic inflammatory disease
  • Skin/ skin-structure infections
  • Syphilis
  • Typhoid fever
  • Post operative infections
  • Prosthetic joint infections
  • Lower respiratory tract infections
  • Epiglottitis

Dosage and Administration:

This medicine has to be administered under medical supervision only.


DOBEX 250 is contraindicated in patients with hypersensitivity towards ceftriaxone, hemolytic anemia, hepatic disorders, Clostridium difficile infections and kidney diseases.

Adverse Effects:

Adverse effects of this medicine include, nausea, vomiting, GI disturbances, pain and swelling in the tongue, headache, and vaginal itching and discharge.


There are no sufficient and well-controlled studies when it comes to ceftriaxone administration in pregnant women and nursing mothers. Therefore, if you are pregnant or nursing, discuss with your doctor about your condition before taking this medicine.


DOBEX 250 injection is available in Vial with WFI with outer carton pack.


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Keep the medicines out of the children’s reach. This product is to be stored as recommended. Do not exceed the recommended dosage. Do not use this information in place of a visit, consultation or advice of your healthcare providers.