Each 10mL of CYTOFATE-O oral suspension contains sucralfate 1000mg and oxetacaine BP 20mg.
CYTOFATE-O is the brand name for the anti-ulcerant combination of sucralfate and oxetacaine. This combination effectively treats different types of ulcers and Helicobacter pylori infections.
Sucralfate is a potent anti-ulcer agent. It works by reacting with HCl acid in the stomach to form a viscous, cross-linking, paste-like material that acts as an acid buffer for approximately 8 hours. Sucralfate is negatively charged and binds to the positively charged proteins that are present at the base of the ulcers. This binding prevents the ulcers from being further damaged and thereby promotes their healing at a faster rate. Sucralfate protects the stomach lining against the damage caused by pepsin, gastric acid and bile acids. This drug also enhances the prostaglandin production; prostaglandins protect the stomach lining.
Oxetacaine acts a mild anesthetic, which relieves the pain that is caused due to different types of ulcers and esophagitis. It also inhibits the gastrin release and decreases the gastric acid secretion. Unlike other anesthetics, oxetacaine does not lose its activity even in strong acidic conditions. It soothes pain, bloating, discomfort and burning sensations that are caused due to ulcers.
5mL four times daily on an empty stomach, one hour before each meal and at bedtime or as advised by the physician
CYTOFATE-O is contraindicated in patients with hypersensitivity towards sucralfate and oxetacaine. Patients with blockages in the intestines, kidney problems, delayed stomach problems and diabetes are recommended not to use this medicine.
The adverse effects associated with this combination are hypersensitivity, nausea, constipation, nervousness, drowsiness, headache, dryness in the mouth, dizziness, fatigue, blurred vision, gastrointestinal disturbances, back pain and rashes.
There are no sufficient and well-controlled studies when it comes to sucralfate and oxetacaine administration in pregnant women and nursing mothers. Therefore, if you are pregnant or nursing, discuss with your doctor about your condition before taking this medicine.
Extra care with the dosage should be taken in patients with breathing problems, kidney diseases, liver diseases, overactive thyroid gland, urination problems, hyper blood pressure and pulmonary complications.
CYTOFATE-O oral suspension is available in 100mL bottle with carton.
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