Zolppi L Capsule

Rabeprazole sodium Levosulpride Tablet

Each capsule contains:

  • Rabeprazole sodium 20 mg
  • Levosulpride 75 mg

DESCRIPTION

Rabeprazole is a rapid acting proton pump inhibitor (PPI). Rabeprazole is a substituted benzimidazole which suppresses gastric acid secretion by inhibiting the gastric H+/ K+ ATPase at the secretory surface of the gastric parietal cell. This enzyme is regarded as the acid (proton) pump within the parietal cell. Rabeprazole blocks the final step of gastric acid secretion.

Levosulpiride is more selective and acts primarily as dopamine D2 antagonist.it is also a moderate agonist at 5-HT receptor.Its 5-HT4 component may enhance its therapeutic efficacy in GI disorders.This property together with antagonism at D2 receptor may contribute to its GI prokinetic effect.

INDICATIONS

GERD,duodenal ulcer,chronic gastritis,irritable bowel syndrome,

DOSAGE & ADMINISTRATION

As prescribed by physician.

CONTRAINDICATIONS

Hypersensitivity,history of epilepsy,alcohol intoxication,phaeocromocytoma,hypokalemia.It indibits gastric acid secretion and may interfere with the absorption of drug swhere gastric pH is an important determinant of bioavailability (ketoconazole,digoxin).

PRECAUTIONS

Caution should be exercised when administering levosulpiride with alcohol,since it can produce increase in sedative effects of alcohol.

Special caution is recommended in case of administering levosulpiride together with psychopharmaceutical drugs, since an increase of undesired effect may occur.

ADVERSE EFFECTS

Headache,dizziness,diarrhea,constipation stomach pain,muscle weakness.

PREGNANCY & LACTATON

Rabeprazole is only recommended for use during pregnancy when benefit outweighs risk. It is recommended that due to the potential for serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

PRESENTATION

ZOLPPI-L capsules are available in 10X10ís Alu Alu pack

CAUTION

The medical information on this site is provided as an information resource only, and is not to be used or relied on for any diagnostic or treatment purposes. This information is not intended to be patient education, does not create any patient-physician relationship, and should not be used as a substitute for professional diagnosis and treatment. Please note it is dangerous to take any medication without doctorís prescription or professional advice from a registered health practitioner. Always read the product directions before use. Do not exceed the recommended dosage. Keep all medicines away from children. Store as recommended. Please consult your health care provider, before making any healthcare decisions or for guidance about a specific medical condition. The allopathic medication and as per the law in India it must be sold by retail pharmacies holding valid trading drug license only.

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