VOMIDIS Tablet

Each tablet contains:

  • Ondansetron 4 mg

DESCRIPTION

Ondansetron is a highly specific and selective serotonin 5-HT3 receptor antagonist and with low affinity for dopamine receptors. The 5-HT3 receptors are present both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone of the area postrema. Serotonin is released by the enterochromaffin cells of the small intestine in response to chemotherapeutic agents and may stimulate vagal afferents (via 5-HT3 receptors) to initiate the vomiting reflex. It is not certain whether ondansetron's antiemetic action is mediated centrally, peripherally, or in both sites.

INDICATIONS

Prevention of nausea and vomiting associated with:

  • Highly emetogenic cancer chemotherapy.
  • Initial and repeat courses of moderately emetogenic cancer chemotherapy,
  • Radiotherapy in patients receiving total body irradiation, single high-dose fraction to the abdomen, or daily fractions to the abdomen.
  • Pregnancy
  • Gastroenteritis

DOSAGE & ADMINISTRATION

As directed by the Physician .

CONTRAINDICATIONS

Ondansetron is contraindicated for patients known to have hypersensitivity to the drug.

PRECAUTIONS

Caution should be exercised when VOMIDIS is prescribed at the same time with apomorphine, cause more serious problem.

VOMIDIS tablet may cause anaphylaxis. It is a life-threatening condition and requires immediate medical attention.

VOMIDIS tablet may cause dizziness. Do not drive or do anything else that could be dangerous.

ADVERSE EFFECTS

Generally ondansetron is well tolerated. However few side effects including headache, diarrhea, fatigue, dizziness and constipation may be seen after ondansetron is administered.

PREGNANCY & LACTATON

It is not known whether ondansetron is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when ondansetron is administered to a nursing woman.

PRESENTATION

It is not known whether ondansetron is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when ondansetron is administered to a nursing woman.

CAUTION

The medical information on this site is provided as an information resource only, and is not to be used or relied on for any diagnostic or treatment purposes. This information is not intended to be patient education, does not create any patient-physician relationship, and should not be used as a substitute for professional diagnosis and treatment. Please note it is dangerous to take any medication without doctor’s prescription or professional advice from a registered health practitioner. Always follow the instructions of physician / doctor / registered medical practitioner before using any medicine. Do not exceed the recommended dosage. Keep all medicines away from your children. Store as recommended. Please consult your health care provider, before making any healthcare decisions or for guidance about a specific medical condition. The allopathic medicine as per the law in India must be sold by retail pharmacies holding valid trading drug license only.

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