It is bactericidal which is active against a wide range of Gram-negative organisms.
Respiratory tract infections, E.N.T Urinary tract, Gynaecological and obstetric infections. Gonorrhoea(When penicillin is unsuitable). Skin soft tissue bone and dental infections.
Adults: 1-4 gm daily in equally divided doses 6 hrly.
Children: 5-15yrs:- 25-50mg/kg body wt. daily in divided doses
Hypersenstivity to cephalo-sporins
Special Precautions: It is well tolerated by patients allergic to penicillin, but cross reaction has been encountered rarely.
Pregnancy: use with caution during early months
Lactation : The drug passes into breast milk
Elderly: Renal impairment may occur
Nausea, vomiting, diarrhoea, Reversible, Neutropenia, Drug rashes Drug interactions: Concurrent treatment with aminoglycosides or potent diuretics(Frusemide ethacrynic acid and piretanide) may adversely affect renal function