Simgesic D

Composition:

Each SIMGESIC-D tablet contains serratiopeptidase 10mg and diclofenac sodium 50mg.

Description:

SIMGESIC-D is an anti-inflammatory and analgesic combination of a non-steroidal anti-inflammatory drug, diclofenac and a proteolytic and fibrinolytic agent, serratiopeptidase. This combination can be used to treat joint inflammation, post-operative pain, swelling, inflammation of the respiratory tract and migraine.

Diclofenac sodium is a drug with strong anti-inflammatory and analgesic properties. Diclofenac blocks the leukocyte migration and the activity of the enzyme - cyclooxygenase (COX-1 and COX-2). Cyclooxygenase or the prostaglandin synthetase is the enzyme that converts arachidonic acid to prostaglandins, leukotrienes and other inflammatory mediators. These inflammatory mediators are associated with pain and swelling and suppressing their production, will relieve the pain.

Serratiopeptidase is an enzyme that is derived from the bacterium, Serratia sp. E-15.Serratiopeptidase hydrolyzes histamines, cytokines, bradykinin and serotonin and eventually reduces the pain and swelling that are associated with the inflammation.

Indications:

  • Joint pain
  • Lower back pain
  • Bone fractures
  • Joint inflammation
  • Pain and swelling associated with the surgeries
  • Migraine
  • Laryngitis
  • Pharyngitis
  • Sore throat
  • Ear infection
  • Thrombophlebitis

Dosage and Administration:

As directed by the physician

Contraindication:

SIMGESIC-D tablets are contraindicated in patients with hypersensitivity towards diclofenac sodium and serratiopeptidase. It is also contraindicated in patients with hepatic impairment, renal impairment, asthma and urticaria.

Adverse effects:

Adverse effects of this medicine include upset stomach, epigastric pain, diarrhea, constipation, nausea, vomiting, GI bleeding, shortness of breath, redness of the skin, liver damage, blisters and toxic epidermal necrolysis.

Precaution:

There are no sufficient and well-controlled studies when it comes to diclofenac and serratiopeptidase administration in pregnant women and nursing mothers. Therefore, if you are pregnant or nursing, discuss with your doctor about your condition before taking this medicine.

Presentation:

SIMGESIC-D tablets are available in 10X10’s blister packing.

Disclaimer:

The medical information on this website is provided as an information resource only. The information on this website is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health provider or a medical practitioner with any questions you may have regarding a medical condition, or to assist in understanding any information or in applying information, that you might have come across, on this website. Please note that it dangerous to take any medication without doctor’s prescription or professional advice from a registered health practitioner. Make sure to follow the instructions of physician/doctor/ registered medical practitioner before using this medicine. Medical and health information changes constantly. Therefore, the information provided on this website should not be considered current, complete or exhaustive. Please consult your healthcare provider, before coming to any conclusions with respect to your health condition or for guidance about a specific medical condition. The allopathic medicine as per the law in India must be sold by retail pharmacies holding valid trading drug license only.

Keep the medicines out of the children’s reach. This product is to be stored as recommended. Do not exceed the recommended dosage. Do not use this information in place of a visit, consultation or advice of your healthcare providers.

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