Each 15g tube POVIRAL cream contains povidone iodine 5%, metronidazole 1% and dexpanthenol 5%.
POVIRAL is the brand name for the topical antimicrobial formulation of metronidazole, povidone iodine and dexpanthenol. This combination effectively works against several skin and skin structure infections that are caused by various microorganisms such as bacteria, viruses, protozoans with least side effects.
In povidone iodine molecule, povidone is said to be the carrier of iodine, which will be exhibiting the microbicidal activity. When released from its complex, the free iodine will kill the microbial cells by penetrating into the cells, disrupting the protein structures and interfering with nucleic acid structure and synthesis. This compound is also said to exhibit anti-inflammatory activity by suppressing the release of inflammatory mediators.
Metronidazole is an anti-bacterial agent that belongs to the class of nitroimidazoles. It works by interfering with the DNA synthesis in anaerobic bacteria. Metronidazole is a prodrug that is reduced to its active form in the anaerobic conditions. This drug binds the bacterial DNA, disrupts its structure, inhibits its replication and eventually leads to the death of the bacterial cells.
Dexpanthenol is a derivative of pantothenic acid. It has high penetrability, due to which, it readily soothes itching and speeds up the wound healing process. It also has an active role in fibroblast proliferation and enhanced re-epithelialization that promote faster wound healing. Dexpanthenol is also said to have strong anti-inflammatory properties.
This medication is to be applied to the skin only. Before applying this product, the affected area must be cleaned and dried. A thin layer of this cream should be applied to the affected area, usually once or twice a day or as directed by your doctor or pharmacist.
This product is contraindicated in patients who are hypersensitive to ingredients present in this medication.
Pregnant and nursing women should talk about their condition to their physician before using this product.
Adverse effects of this medication include skin rashes, redness, swelling, irritation and hives.
Store this product at 25°C and it should be kept away from direct sunlight and heat. This product should be kept out of reach of children. Make sure to keep the tube tightly closed when not in use.
POVIRAL cream is available as a 15g tube.
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Keep the medicines out of the children’s reach. This product is to be stored as recommended. Do not exceed the recommended dosage. Do not use this information in place of a visit, consultation or advice of your healthcare providers.