15g tube of NOLLDERM 5 cream contains clobetasol propionate IP - 0.05%, gentamicin IP - 0.1%,tolnafate IP - 1%, iodochlorhydroxyquinoline IP - 1% and clotrimazole IP - 1%
NOLLDERM 5 is a unique and powerful anti-bacterial, anti-fungal and anti-inflammatory topical formulation that addresses various bacterial and fungal infections and eases the inflammatory symptoms.
Clobetasol is one of the very few potent topical corticosteroids. It acts as an agonist of corticosteroid hormone receptor. It relieves the inflammatory symptoms by suppressing the levels of the inflammatory mediators like leukotrienes and prostaglandins that are released at the site of infection during the inflammatory reaction.
Gentamicin is an antibacterial agent that belongs to the class of aminoglycosides. It works by blocking the protein synthesis in bacteria, which leads to the production of toxic and non-functional proteins and eventually cause the death of the bacterial cells. Gentamicin binds to 30S-subunit proteins and 16S rRNA, which hampers the functions of the initiation complex that eventually leads to mRNA misreading.
Tolnaftate is a powerful anti-fungal agent that addresses common fungal infections like jock itch and ringworm by interfering with the cell wall synthesis in fungal cells and thereby killing them.
Iodochlorhydroxyquinoline is an antifungal and antiprotozoal agent that is derived from hydroxyquinoline. This drug addresses skin infections that are caused due to protozoans and fungi.
Clotrimazole is a broad-spectrum antifungal agent that works by blocking the biosynthesis of ergosterol - the key component of fungal cell walls and prevents their growth.
NOLLDERM 5 cream is meant for external application only. Before applying this product, the affected area must be cleaned and dried. A thin layer of this cream should be applied to the affected area, usually once or twice a day or as directed by your doctor or pharmacist.
Adverse effects of this product include burning or itching sensation of skin, redness, swelling, peeling, dryness, and irritation.
Store this product at 25oC and it should be kept away from direct sunlight and heat. This product should be kept out of reach of children. Make sure to keep the tube tightly closed when not in use.
NOLLDERM 5 cream is available as a 15g tube.
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Keep the medicines out of the children’s reach. This product is to be stored as recommended. Do not exceed the recommended dosage. Do not use this information in place of a visit, consultation or advice of your healthcare providers.