Nevimox-SB 1000 Tablets

Nevimox-SB 1000 Tablets

Composition:

Each tablet of NEVIMOX-SB 1000 contains amoxicillin 500mg and sulbactam 500mg.

Description:

NEVIMOX-SB 1000 is the brand name for the antibiotic combination of amoxicillin and the beta-lactamase inhibitor, sulbactam. This oral medication is effective against the broad spectrum of micro-organisms. NEVIMOX-SB 1000 works by preventing the cell wall synthesis and is bactericidal in nature.

Amoxicillin:

Amoxicillin belongs to the class of aminopenicillins and is a beta-lactam antibiotic. Like other beta-lactam antibiotics, this drug binds to specific Penicillin Binding Proteins (PBPs) that are present within the cell envelope of the bacterial cells. The penicillin-sensitive transpeptidase-C terminal domain of the PBPs is acylated by the amoxicillin and the domain becomes inactivated. This leads to the inhibition of cross-linkage between the linear peptidoglycan polymer chains, which in turn lead to bacterial cell death. Amoxicillin is not resistant to beta-lactamase activity and is prone to ready degradation by the enzyme. Therefore, it has to be administered with beta-lactamase inhibitors like sulbactam.

Sulbactam:

Sulbactam is an effective beta-lactamase inhibitor, whose function is to prevent the degradation of amoxicillin by the beta-lactamase enzyme present within the bacterial cell wall. Like amoxicillin, sulbactam also possesses a beta-lactam ring which binds to the beta-lactamase enzyme and prevents the enzyme’s binding to the beta-lactam ring of the antibiotic, amoxicillin.

Indications:

  • General bacterial infections
  • Anthrax
  • Bacterial Endocarditis
  • Pneumonia
  • Skin/ Skin structure infections
  • Typhoid fever and salmonella infections
  • Chlamydial Urogenital infection
  • Upper and lower respiratory tract infections
  • Community-acquired pneumonia
  • Genitourinary infection
  • Ulcers
  • Gonorrhea
  • Acute otitis media
  • Lyme disease
  • Non-gonococcal urethritis
  • Listerial meningitis

Dosage and Administration:

As directed by the physician

Contraindications:

NEVIMOX-SB 1000 tablets are contraindicated in patients with hypersensitivity towards its ingredients and penicillins. It is also contraindicated in patients with hepatic impairment, renal impairment and Clostridium difficile bacterial infection.

Adverse effects:

Adverse effects of this medication are nausea, vomiting, diarrhea, chest pain, painful urination, impaired liver functions, loss of appetite, abdominal pain, sore throat and body aches.

Precautions:

There are no sufficient and well-controlled studies when it comes to amoxicillin administration in pregnant women and nursing mothers. Therefore, if you are pregnant or nursing, discuss with your doctor about your condition before taking this medicine.

Presentation:

NEVIMOX-SB 1000 tablets are available in 10X10’s Alu Alu packing.

Disclaimer:

The medical information on this website is provided as an information resource only. The information on this website is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health provider or a medical practitioner with any questions you may have regarding a medical condition, or to assist in understanding any information or in applying information, that you might have come across, on this website. Please note that it dangerous to take any medication without doctor’s prescription or professional advice from a registered health practitioner. Make sure to follow the instructions of physician/doctor/ registered medical practitioner before using this medicine. Medical and health information changes constantly. Therefore, the information provided on this website should not be considered current, complete or exhaustive. Please consult your healthcare provider, before coming to any conclusions with respect to your health condition or for guidance about a specific medical condition. The allopathic medicine as per the law in India must be sold by retail pharmacies holding valid trading drug license only.

Keep the medicines out of the children’s reach. This product is to be stored as recommended. Do not exceed the recommended dosage. Do not use this information in place of a visit, consultation or advice of your healthcare providers.

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