Each FORPPI TOTAL capsule contains:
FORPPI TOTAL is the brand name for the anti-ulcerant and antiemetic combination that effectively treats various complications associated with acid reflux and ulcers by reducing the acid secretion, easing the movement of the food through GI tract and regulating the dopamine receptors.
Pantoprazole is a substituted benzimidazole and is a proton pump inhibitor. Pantoprazole blocks the H+/K+ ATPase enzyme system or the proton pump system present on the surface of the gastric parietal cells. Pantoprazole inhibits the final step of gastric acid production, i.e., the inward movement of H+ ions into the gastric lumen, and eventually reduces the levels of gastric acid in the stomach and its reflux towards the chest region.
Itopride works as a prokinetic agent, an antagonist of dopamine (D2) receptor and a motility stimulant. Itopride maintains high levels of acetylcholine, which is important for esophageal and GI peristalsis, to increase the pressure in the lower esophageal sphincter, stimulate the gastric motility and lastly, to improve the gastro-duodenal coordination. At chemoreceptor trigger zone (CTZ) in the medulla oblongata, itopride acts as an antagonist of D2 dopamine receptors and suppresses the urge to vomit.
As directed by the physician
This medicine shouldn’t be crushed and chewed in the mouth; instead, it should be swallowed whole.
FORPPI TOTAL capsules are contraindicated in patients with hypersensitivity towards pantoprazole and itopride. This medicine is also contraindicated in patients with hepatic and renal impairment, interstitial nephritis, congestive heart failure and Clostridium difficile infections.
Adverse effects of this medicine include headache, dizziness, blurred vision, diarrhea, severe itching in the skin, rashes and swelling.
There are no sufficient and well-controlled studies when it comes to pantoprazole and itopride administration in pregnant women and nursing mothers. Therefore, if you are pregnant or nursing, discuss with your doctor about your condition before taking this medicine.
FORPPI TOTAL capsules are available in 10X10’s Alu Alu packing.
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Keep the medicines out of the children’s reach. This product is to be stored as recommended. Do not exceed the recommended dosage. Do not use this information in place of a visit, consultation or advice of your healthcare providers.