Pantoprazole is a proton pump inhibitor that decreases the amount of acid produced in the stomach. It suppresses the final step in gastric acid production by covalently binding to the enzyme system at the secretory surface of the gastric parietal cell. This effect leads to inhibition of both basal and stimulated gastric acid secretion, irrespective of the stimulus. The binding to the enzyme system results in duration of antisecretory effect that persists longer than 24 hours.
Dyspepsia ,peptic ulcer disease including after endoscopic treatment for bleeding ,as part of Helicobacter pylori eradication therapy,Gastroesophageal reflux disease (GERD or GORD) esophagus, Stress gastritis and ulcer prevention in critical care , Gastrinomas and other conditions that cause hyper secretion of acid including Zollinger–Ellison syndrome .
FORPPI-40 mg ,one tablet should be taken daily for four to eight weeks of treatment. The medication should be taken around the same time each day.
FORPPI-40 should not be administered in the following cases:
Caution should be exercised when patient is hypersensitive to pantoprazole or to similar drugs (such as lansoprazole, omeprazole); or if you have any other allergies.
Proton pump inhibitors (such as pantoprazole) may increase risk for bone fractures, especially with longer use, higher doses, and in older adults.
Severe stomach pain, nausea, vomiting, and weight loss, diarrhea that is watery or bloody, seizure (convulsions), kidney problems - urinating more or less than usual, blood in urine, swelling, rapid weight gain, symptoms of low magnesium - dizziness, confusion; fast or uneven heart rate, tremors (shaking) or jerking muscle movements, feeling jittery, muscle cramps, muscle spasms in your hands and feet , cough or choking feeling.
Although there is no evidence suggesting that pantoprazole use is harmful during pregnancy.It is recommended that the drug only be used during pregnancy as needed, when no other options are available.
FORPPI-40 mg tablets are available in a 10X10’s blister packing
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