FEXODIS-M Tablet

Each tablet contains:

  • Fexofenadine 120 mg
  • Montelukast 10 mg

DESCRIPTION

Fexofenadine is an active metabolite of terfenadine, is a second-generation, long lasting H1-receptor antagonist which has a selective and peripheral H1-antagonistic action. Fexofenadine blocks the H1-receptor and thus prevents activation of cells by histamine in the GI tract, large blood vessels and bronchial smooth muscle. This leads to relief of the allergic symptoms.

Montelukast is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotriene CysLT1 receptor. Cysteinyl leukotrienes and leukotriene receptor occupation have been correlated with the pathophysiology of asthma ( such as, airway edema, smooth muscle contraction and altered cellular activity associated with the inflammatory process, which contribute to the signs and symptoms of asthma).

INDICATIONS

Asthma, chronic allergy, seasonal allergy, hay fever.

DOSAGE & ADMINISTRATION

As directed by the physician.

CONTRAINDICATIONS

Hypersensitivity, patients with blood and lymphatic system disorder and psychiatric disorder.

PRECAUTION

Patients with known aspirin sensitivity should continue avoidance of aspirin or other NSAID, while taking Montelukast.

Montelukast is not indicated for use in the reversal of bronchospasm in acute asthma attacks

ADVERSE EFFECTS

The most commonly reported adverse events are headache, drowsiness, nausea, and dizziness, viral infection (cold/flu),dizziness, fatigue; nausea, dyspepsia, dysmenorrhoea.

PREGNANCY & LACTATON

For montelukast, there is limited human data available. It is most likely compatible.

There are no controlled data in human pregnancy. Fexofenadine is only recommended for use during pregnancy when benefit outweighs risk.

PRESENTATION

FEXODIS-M tablets are available in a 10X10ís strip packing

CAUTION

The medical information on this site is provided as an information resource only, and is not to be used or relied on for any diagnostic or treatment purposes. This information is not intended to be patient education, does not create any patient-physician relationship, and should not be used as a substitute for professional diagnosis and treatment. Please note it is dangerous to take any medication without doctorís prescription or professional advice from a registered health practitioner. Always follow the instructions of physician / doctor / registered medical practitioner before using any medicine. Do not exceed the recommended dosage. Keep all medicines away from your children. Store as recommended. Please consult your health care provider, before making any healthcare decisions or for guidance about a specific medical condition. The allopathic medicine as per the law in India must be sold by retail pharmacies holding valid trading drug license only.

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