Dobex 500 Injection

Composition

Ceftriaxone 500mg

Description:

DOBEX 500 is the brand name for the beta-lactam antibiotic-ceftriaxone. Ceftriaxone is the third generation cephalosporin drug that works by interfering with the cell wall synthesis in bacteria. It is effective against several gram +ve bacteria, due to its high penetrability and longer half-life. This drug is resistant to beta-lactamase, penicillinases and cephalosporinases activity.

Mechanism of Action:

Ceftriaxone, which has a beta-lactam ring, binds to the penicillin-binding proteins (PBPs) present in the bacterial cell wall. This binding is followed by a series of reactions, and ultimately the transpeptidation step is blocked. This leads to the leakage of the cell contents and ultimately causes to the death of the bacterial cells.

Indications:

  • Community-acquired pneumonia
  • Congenital gonococcal conjunctivitis
  • Endocarditis
  • Gonorrhea
  • Lyme disease
  • Meningitis
  • Otitis Media
  • Pelvic inflammatory disease
  • Skin/ skin-structure infections
  • Syphilis
  • Typhoid fever
  • Post operative infections
  • Prosthetic joint infections
  • Lower respiratory tract infections
  • Epiglottitis

Dosage and Administration:

This medicine has to be administered under medical supervision only.

Contraindication:

DOBEX 500 is contraindicated in patients with hypersensitivity towards ceftriaxone, hemolytic anemia, hepatic disorders, Clostridium difficile infections and kidney diseases.

Adverse Effects:

Adverse effects of this medicine include, nausea, vomiting, GI disturbances, pain and swelling in the tongue, headache, and vaginal itching and discharge.

Precaution:

There are no sufficient and well-controlled studies when it comes to ceftriaxone administration in pregnant women and nursing mothers. Therefore, if you are pregnant or nursing, discuss with your doctor about your condition before taking this medicine.

Presentation:

DOBEX 500 injection is available in Vial with WFI with outer carton pack.

Disclaimer:

The medical information on this website is provided as an information resource only. The information on this website is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health provider or a medical practitioner with any questions you may have regarding a medical condition, or to assist in understanding any information or in applying information, that you might have come across, on this website. Please note that it dangerous to take any medication without doctor’s prescription or professional advice from a registered health practitioner. Make sure to follow the instructions of physician/doctor/ registered medical practitioner before using this medicine. Medical and health information changes constantly. Therefore, the information provided on this website should not be considered current, complete or exhaustive. Please consult your healthcare provider, before coming to any conclusions with respect to your health condition or for guidance about a specific medical condition. The allopathic medicine as per the law in India must be sold by retail pharmacies holding valid trading drug license only.

Keep the medicines out of the children’s reach. This product is to be stored as recommended. Do not exceed the recommended dosage. Do not use this information in place of a visit, consultation or advice of your healthcare providers.

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