Each tablet of DEXOCAN-150 contains fluconazole 150mg.
DEXOCAN-150 is the brand name for the anti-fungal agent fluconazole. Fluconazole belongs to the class of imidazoles and is of synthetic origin. This drug works by inhibiting the cell wall synthesis in the fungal cells. Ergosterol is the key component of the fungal cell wall, whose function is to maintain the cellular integrity and fluconazole prevents its synthesis from lanosterol. Fluconazole effectively fights against fungal infections such as candidiasis, skin irritation and itching.
Fluconazole inhibits the activity of 14-a demethylase, a cytochrome P-450 enzyme, which converts lanosterol into ergosterol. This results in increased cellular permeability, which ultimately leads to the leakage of cell contents and death of the fungal cells. Other mechanisms by which fluconazole prevents the growth of fungal cells are endogenous respiration inhibition, purine intake inhibition, impaired phospholipid synthesis and inhibition of transformation of yeasts to mycelial forms.
As directed by the physician. Administered dosage is to be completed, in order to avoid the recurrence of the infection.
This medicine is contraindicated in patients with hypersensitivity towards fluconazole, hepatic disorders, cardiac disorders and kidney diseases.
Adverse effects of this medicine include upper stomach pain, loss of appetite, dark urine, fever and chills, body aches, skin rashes, weakness, nausea and vomiting.
Avoid this medicine during pregnancy and nursing.
DEXOCAN-150 tablets are available in 50X1’s blister packing.
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