Sucralfate is a locally acting substance reacts with hydrochloric acid in the stomach to form a cross-linking, viscous, paste-like material capable of acting as an acid buffer after a single dose. It also attaches to proteins on the surface of ulcers, such as albumin and fibrinogen, to form stable insoluble complexes. These complexes serve as protective barriers at the ulcer surface, preventing further damage from acid, pepsin, and bile.Thus acts as anti-ulcerant.
Oxetacaine is a local anesthetic of the amide type. It produces a reversible loss of sensation by preventing or diminishing the conduction of sensory nerve impulses near the site of its application.
It also decreases the permeability of the nerve cell membrane to sodium ions by membrane stabilising effect. Relieves pain, bloating, discomfort, and fullness.
Peptic ulcer,active duodenal ulcers, GERD,Stress ulcer prophylaxis,Helicobacter pylori infection
5ml four times daily on an empty stomach, one hour before each meal and at bed time.
Contraindicated in patients with proven allergy to any ingredient.
Patient having kidney problems or are on dialysis, or have blockage of the intestines, delayed stomach emptying, or difficulty swallowing CYTOFATE-O Liquid is not recommended.
Patient receiving tube feedings.
Systemic AI toxicity may occur in patients with chronic renal failure.
Bone growth and neurologic status should be monitored.
Constipation, diarrhea, nausea, dizziness, dry mouth, GI disturbances, rash, pruritis, headache, vertigo, back pain & drowsiness, Nervousness, Blurred vision.
There are no controlled data in human pregnancy. There are no data on the excretion of sucralfate into human milk.
CYTOFATE-O Liquid contains Sucralfate 1 gm/10ml and Oxetacaine 20mg. The total content in each bottle is 100 ml.
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