CLobadis MN Cream

Topical anti-inflammatory cream

Composition

Clobetasol propionate

U.S.P

0.05% W/W

Miconazole Nitrate

I.P

2% W/W

Neomycin Sulphate

I.P.

 

Eq. to Neomycin

 

0.05% W/W

Chlorocressol

I.P

0.1%W/W

In a cream base

 

q.s

 

DESCRIPTION

CLobadis MN Cream is a skin ointment. A combination of Clobetasol Propionate, Miconazole Nitrate, Neomycin & Zinc Sulphate. Clobetasol Propionate is a highly active corticosteroid. Miconazole is an imidazole antifungal agent. Neomycin is an aminoglycoside antibiotic.

MECHANISM OF ACTION

Clobetasol Propionate has topical anti-inflammatory activity. The major effect on skin is a non-specific anti-inflammatory response, partially due to vasoconstriction and decrease in collagen synthesis. Miconazole works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes. Neomycin is a broad-spectrum antibiotic.

INDICATIONS

Corticosteroid-responsive dermatoses, eczema and psoriasis.

CONTRAINDICATIONS

Long-term treatment of ulcerative conditions, rosacea, pruritus, presence of acute infections. Hypersensitivity.

SIDE EFFECTS

Prolonged usage of large amount of Clobetasol Propionate can lead to sufficient systemic levels to produce adrenal suppression, Cushing's syndrome, diabetes and hypertension.

PRECAUTIONS

Heart failure, recent myocardial infarction, hypertension, diabetes mellitus, epilepsy, glaucoma, hypothyroidism, hepatic failure, renal impairment, psychoses, children and elderly.

DIRECTIONS

To be applied as directed by the physician.

Direction to use:

  • Keep in a cool, dry place away from direct heat and light.
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