Each 1g sachet of CHOFIX contains cholecalciferol 60000 IU.
Cholecalciferol or vitamin D3 is a steroid hormone, which is one of the fat-soluble vitamins. Vitamin D3, as a health supplement promotes bone health and its deficiency leads to weak bones, bone pain, fractures, weak muscles, stunted growth and dental problems.
Calcitriol (1, 25-dihydroxycholecalciferol) is the active form of vitamin D3, which has a crucial role in the maintenance of potassium and calcium levels in the blood and bone mineralization. Calcitriol modulates the gene expression by binding to the vitamin D receptors. Vitamin D3 is important for the absorption of phosphorus and calcium in the intestine and renal resorption of calcium. As a health supplement, cholecalciferol prevents vitamin D deficiency and the diseases associated with it. It is also used for the treatment of hypophosphatemia and hypoparathyroidism that leads to low serum calcium.
Cholecalciferol is an inactive molecule, and it is activated by two hydroxylation reactions. The first hydroxylation reaction happens in the liver in order to synthesize 25-hydroxycholecalciferol from cholecalciferol. The second hydroxylation happens in the kidney, where the 25-hydroxycholecalciferol is converted to 1, 25-hydroxycholecalciferol (calcitriol). All the metabolites that are involved in these reactions bind to the vitamin D-binding protein, present in the blood and are transported to numerous target tissues.
As directed by the physician or nutritionist
CHOFIX granules are contraindicated in patients with hypersensitivity towards its ingredients. This health supplement is also contraindicated in patients with sarcoidosis, high levels of phosphate and calcium in the blood, high levels of vitamin D in the body, arteriosclerosis and reduced kidney functions.
Adverse effects of this health supplement include rashes, itching, swelling of the face, throat and tongue, dizziness, trouble in breathing, irregular heartbeat, dry mouth, headache, vomiting, fatigue and tiredness.
Cholecalciferol is well tolerated among pregnant and nursing women when administered as per the recommended dosage.
If you are any prior health condition, it is better to discuss it with your doctor before using this product.
This product is also available in the injection form under pharmaceuticals category.
Product name: CHOFIX injection – cholecalciferol 600000 IU
CHOFIX sachets are available in 10(sachets) X1g box packing.
Always read the product directions before use. Do not exceed the recommended intake. If you suffer from food allergies, make sure you to talk to your healthcare professional before using this product. Vitamin, amino acid or mineral supplements are not intended to treat or prevent any disease. Food supplements must not replace a balanced and varied diet and a healthy lifestyle. Healthcare and lifestyle information changes constantly. Therefore, the information provided on this website should not be considered current, complete or exhaustive. Please consult your healthcare professional, before coming to any conclusions with respect to your health condition. Properly discard this supplement when it is expired or no longer needed.