Cholecalciferol (vitamin D3) – 600000 IU
Cholecalciferol is a biomolecule derived from cholesterol and it is the naturally occurring form of vitamin D. Regulation of calcium and phosphorous levels in the blood is the key function of vitamin D3. CHOFIX administration is helpful in the treatment of vitamin D deficiency and other health conditions caused due to the deficiency of vitamin D. Common causes for vitamin D deficiency include kidney or liver disorders, inadequate sunlight exposure and genetic defects in the vitamin D receptors.
Cholecalciferol is an inactive molecule, and it is activated by two hydroxylation reactions. The first hydroxylation reaction happens in the liver in order to synthesize 25-hydroxycholecalciferol from cholecalciferol. The second hydroxylation happens in the kidney, wherein the 25-hydroxycholecalciferol is converted to 1, 25-hydroxycholecalciferol, which is also known as the calcitriol. Vitamin D receptor regulates the activity of calcitriol in the body.
Calcitriol increases the serum concentration of calcium by increasing the absorption of calcium and potassium in the gastrointestinal tract, increasing distal renal tubular reabsorption and improving the osteoclastic reabsorption rate.
CHOFIX injection is to be administered under medical supervision only.
CHOFIX injection is contraindicated in patients with hypersensitivity towards its ingredients. It is also contraindicated in patients with sarcoidosis, high levels of phosphate and calcium in the blood, high levels of vitamin D in the body, arteriosclerosis and reduced kidney functions.
Adverse effects of this health supplement include rashes, itching, swelling of the face, throat and tongue, dizziness, trouble in breathing, irregular heartbeat, dry mouth, headache, vomiting, fatigue and tiredness.
Cholecalciferol is well tolerated among pregnant and nursing women when administered as per the recommended dosage.
If you are any prior health condition, it is better to discuss it with your doctor before using this product.
CHOFIX injection is available in 20mL& 10 mL WFI pack.
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Keep the medicines out of the children’s reach. This product is to be stored as recommended. Do not exceed the recommended dosage. Do not use this information in place of a visit, consultation or advice of your healthcare providers.