CEFDIS-CV Tablet

Each tablet contains:

  • Cefixime - 200 mg
  • Clavulanic acid - 125 mg

DESCRIPTION

Cefixime is a semi-synthetic, broad spectrum cephalosporin antibiotic of third generation for oral administration. It is a bactericidal antibiotic, kills bacteria by interfering in the synthesis of the bacterial cell wall. Cefixime is highly stable in the presence of beta-lactamase enzymes. Cefixime has marked in-vitro bactericidal activity against a wide variety of Gram-positive and Gram-negative organisms including beta lactamase producers.

Clinical efficacy of Cefixime has been demonstrated in infections caused by commonly occurring pathogens including Gram-positive organism Streptococcus pneumoniae, Streptococcus pyogenes, Gram-negative organism Escherichia coli, Proteus mirabilis, Klebsiella spp., Haemophilus influenzae (beta-lactamase positive and negative), Moraxella catarrhalis (beta-lactamase positive and negative), Salmonella typhi and Enterobacter species.

Clavulanic acid competitively and irreversibly inhibits a wide variety of beta-lactamases, commonly found in microorganisms resistant to penicillins and cephalosporins. Binding and irreversibly inhibiting the beta-lactamase results in a restoration of the antimicrobial activity of beta-lactam antibiotics against lactamase-secreting-resistant bacteria. By inactivating beta-lactamase, the accompanying cephalosporin Cefixime may be made more potent.

INDICATIONS

  • Pharyngitis, Tonsillitis, Otitis Media
  • Uncomplicated community-acquired pneumonia and infections by non-Ampc ESBL.
  • Acute Bronchitis and Acute exacerbations of chronic bronchitis
  • Uncomplicated Urinary Tract Infections
  • Uncomplicated ano-genital gonorrhea.

DOSAGE & ADMINISTRATION

As directed by the physician.

CONTRAINDICATIONS

Cefixime is contraindicated in patients with known sensitivity or allergies to cephalosporin class of antibiotics. As Cefixime is a third generation cephalosporin, it is not contraindicated for patients with a true penicillin allergy.

PRECAUTIONS

Because azithromycin is principally eliminated via liver.caution should be exercised when it is administered to patients with impaired hepatic function.

PRECAUTIONS

liver disease (including liver problems caused by previous use of amoxicillin/clavulanic acid), kidney disease (such as requiring dialysis), a certain type of viral infection (infectious mononucleosis).

This product may cause live bacterial vaccines (such as typhoid vaccine) not to work as well. Therefore, do not have any immunizations/vaccinations while using this medication without the consent of your doctor.

ADVERSE EFFECTS

  • Diarrhea that is watery or bloody
  • Chest pain, uneven heartbeats
  • Nausea, stomach pain, low fever, loss of apetite,dark urine, clay-colored stools, jaundice
  • Severe skin reaction: fever, sore throat, swelling in face or tongue, burning in eyes and skin

PREGNANCY & LACTATON

Cefixime :Single dose of cefixime is considered safe in pregnancy

Azithromycin:Limited data in pregnancy; use only if potential benefit outweighs risk.

PRESENTATION

CEFDIS-AZ tablets are available in a 10X10ís Alu Alu packing.

CAUTION

The medical information on this site is provided as an information resource only, and is not to be used or relied on for any diagnostic or treatment purposes. This information is not intended to be patient education, does not create any patient-physician relationship, and should not be used as a substitute for professional diagnosis and treatment. Please note it is dangerous to take any medication without doctorís prescription or professional advice from a registered health practitioner. Always follow the instructions of physician / doctor / registered medical practitioner before using any medicine. Do not exceed the recommended dosage. Keep all medicines away from your children. Store as recommended. Please consult your health care provider, before making any healthcare decisions or for guidance about a specific medical condition. The allopathic medicine as per the law in India must be sold by retail pharmacies holding valid trading drug license only.

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