Binadis-250 Tablets

Binadis-250 Tablets

Composition:

Each BINADIS-250 tablet contains terbinafine 250mg.

Description:

Terbinafine is a synthetic antifungal agentthat belongs to the family of allylamines. Terbinafine is used both orally and topically against a wide range of fungal infections. It is largely used to treat ringworm, fungal nail infections and pityriasis versicolor.

Mechanism of action:Terbinafine’s mechanism of action involves the inhibition of the enzyme, squalene epoxidase’s activity. This enzyme is essential for the first oxygenation step of sterol (ergosterol) synthesis. Squalene is converted to lanosterol in the first step which is then converted to ergosterol; but, terbinafine prevents the synthesis of lanosterol. Inhibiting the activity of squalene epoxidase would lead to deposition of high concentration of squalene within the cell. High concentration of squalene interferes with the membrane function and cell wall formation. The end result of this inhibition is that the fungal cells become ergosterol deficient, and their cell wall is broken down, which eventually leads to their death and prevents further infections.

Indications:

  • Dermatophyte infections
  • Pityriasis versicolor
  • Tineacapitis
  • Tineacorporis
  • Tineacruris
  • Tineapedis

Dosage and Administration:

As directed by the physician

Contraindications:

BINADIS-250 is contraindicated in patients with hypersensitivity towards terbinafine. It is also contraindicated in patients with hepatic impairment, compromised immune system and psoriasis.

Adverse effects:

Adverse effects of this medication are dyspepsia, abdominal pain, diarrhea, flatulence, nausea, urticaria, pruritus, urticaria, taste disturbances and liver test abnormalities.

Precautions:

There are no sufficient and well-controlled studies when it comes to terbinafine administration in pregnant women and nursing mothers. Therefore, if you are pregnant or nursing, discuss with your doctor about your condition before taking this medicine.

Presentation:

BINADIS-250 tablets are available in 10X10’s blister packing

Disclaimer:

The medical information on this website is provided as an information resource only. The information on this website is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health provider or a medical practitioner with any questions you may have regarding a medical condition, or to assist in understanding any information or in applying information, that you might have come across, on this website. Please note that it dangerous to take any medication without doctor’s prescription or professional advice from a registered health practitioner. Make sure to follow the instructions of physician/doctor/ registered medical practitioner before using this medicine. Medical and health information changes constantly. Therefore, the information provided on this website should not be considered current, complete or exhaustive. Please consult your healthcare provider, before coming to any conclusions with respect to your health condition or for guidance about a specific medical condition. The allopathic medicine as per the law in India must be sold by retail pharmacies holding valid trading drug license only.

Keep the medicines out of the children’s reach. This product is to be stored as recommended. Do not exceed the recommended dosage. Do not use this information in place of a visit, consultation or advice of your healthcare providers.

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